تفاصيل الوثيقة

نوع الوثيقة : مقال في مؤتمر 
عنوان الوثيقة :
Role of miRNAs in human cancer metastasis: Implications for therapeutic intervention.
Role of miRNAs in human cancer metastasis: Implications for therapeutic intervention.
 
لغة الوثيقة : الانجليزية 
المستخلص : tMetastasis is the spread and growth of localized cancer to new locations in the body and is consideredthe main cause of cancer-related deaths. Metastatic cancer cells display distinct genomic and epigenomicprofiles and almost universally an aggressive pathophysiology. A better understanding of the molecu-lar mechanisms and regulation of metastasis, including how metastatic tumors grow and survive in thenascent niche and the interactions of the emergent metastatic cancer cells within the local microenviron-ment may provide tools to design strategies to restrict metastatic dissemination. Aberrant microRNAs(miRNA) expression has been reported in metastatic cancer cells. MicroRNAs are known to regulatedivergent and/or convergent metastatic gene pathways including activation of reprogramming switchesduring metastasis. An in-depth understanding of role of miRNAs in the metastatic cascade may lead tothe identification of novel targets for anti-metastatic therapeutics as well as potential candidate miRNAsfor cancer treatment. This review primarily focuses on the role of miRNAs in the mechanisms of cancermetastasis as well as implications for metastatic cancer treatment. 
اسم المؤتمر : Seminars in Cancer Biology 
سنة النشر : 1438 هـ
2017 م 
عدد الصفحات : 15 
نوع المقالة : مقالة علمية 
الجهة المنظمة : Elsevier 
تاريخ الاضافة على الموقع : Tuesday, May 16, 2017 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
Mohammad Alam JafriJafri, Mohammad Alamباحث رئيسيدكتوراه 
Mohammed Hussein Al-QahtaniAl-Qahtani, Mohammed Husseinباحثدكتوراه 
Jerry William ShayShay, Jerry Williamباحثدكتوراه 

الملفات

اسم الملفالنوعالوصف
 40750.pdf pdf 

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